What are the units of KI?
What are the units of KI?
Ki is the inhibition constant, expressed in the same units as I, which you entered into the column titles. Vmax is the maximum enzyme velocity, in the absence of inhibitor, expressed in the same units as Y. Km is the Michaelis-Menten constant, expressed in the same units as X.
What is KD equal to?
Therefore, Kd is equal to the ratio of the dissociation rate constant (k-1) and the association rate constant (k1). Dissociation is a unimolecular process, while association is bimolecular, accounting for the molarity unit of Kd.
Is KD a km?
Kd and Km represent different things. Km is a measure of affinity, and is the concentration of substrate that reaches 1/2 Vmax. Kd, however, is the dissociation constant, and measures the dissociation of the substrate from the ES complex. Therefore, the larger Kd is, the less affinity the enzyme has for the substrate.
What is a good IC50?
In most cases, the IC50 of the best candidate compound should be lower to 10 micromolar, acceptable for NIH to screen the NCI60 program. In addition, the drug design should think over the related problem about the absorption, distribution, metabolism and excretion in our body.
What is MTT full form?
MTT
| Acronym | Definition |
|---|---|
| MTT | Mobile Training Team |
| MTT | Molecular Targeted Therapies (oncology) |
| MTT | Multi-Table Tournament (poker) |
| MTT | Methods, Techniques and Tools (software) |
Is MTT toxic to cells?
Toxicity. Although it is widely used, the MTT reagent exhibits cytotoxic effects, and adding the reagent to estimate cell viability may actually be damaging or even killing cells during the course of an experiment. MTT has been reported to be toxic to eukaryotic cells (10).
What is MTT reagent?
Useful in the study of cell & mitochondrial health, MTT is a pale yellow substrate that is cleaved by living cells to yield a dark blue formazan product. More>> Useful in the study of cell & mitochondrial health, MTT is a pale yellow substrate that is cleaved by living cells to yield a dark blue formazan product.
What does MTT stand for Star Wars?
Multi Troop Transport