What is the RF of aspirin?

What is the RF of aspirin?

The Rf values are 0.70 for salicylic acid and diflunisal, 0.67 for aspirin and methyl salicylate, 0.60 for gentisic acid, 0.57 for p-aminosalicyclic acid, and 0.40 for salicyluric acid.

Is aspirin more polar than acetaminophen?

Acetaminophen has two hydrogen bonds and one dipole-dipole making it more polar than Aspirin, Phenacetin, and Ibuprofen.

How do you calculate RF?

The Rf value of a compound is equal to the distance traveled by the compound divided by the distance traveled by the solvent front (both measured from the origin).

What devices use RF?

Modern devices often generate electromagnetic fields of radio frequency (RF) ranging from 100 kHz to 300 GHz. Key sources of RF fields include mobile phones, cordless phones, local wireless networks and radio transmission towers. They are also used by medical scanners, radar systems and microwave ovens.

What affects Rf value?

Retention Factor Rf values and reproducibility can be affected by a number of different factors such as layer thickness, moisture on the TLC plate, vessel saturation, temperature, depth of mobile phase, nature of the TLC plate, sample size, and solvent parameters. These effects normally cause an increase in Rf values.

Which pigment has the lowest RF value?

carotenes

How do you know if separated pigment spots?

How could you find out whether the separated pigment spots you have observed on your chromatogram are single, pure pigments or a mixture of two or more? Use a different solvent and/or a different stationary phase, this means pigments which may have run together will separate out.

Why does carotene have a high RF value?

The Rf value of the xanthophyll is two thirds that of carotene because xanthophyll has an H bond with cellulose, which slows it down, and makes it less soluble in the solvent. Carotene is more soluble in 9:1 petroleum-ether acetone solution, which caused it to be carried higher and have a larger Rf value.

What are the 2 phases of chromatography?

Chromatography is essentially a physical method of separation in which the components of a mixture are separated by their distribution between two phases; one of these phases in the form of a porous bed, bulk liquid, layer or film is generally immobile (stationary phase), while the other is a fluid (mobile phase) that …

What are the disadvantages of chromatography?

Disadvantages Of Column Chromatography –

  • It is a time-consuming process for the separation of compounds.
  • It is expensive as higher quantities of solvents are required.
  • The automated process becomes complicated and therefore costly.
  • It has a low separation power.