What does NaNH2 do to an alkyne?

What does NaNH2 do to an alkyne?

As a strong base, NaNH2 will deprotonate alkynes, alcohols, and a host of other functional groups with acidic protons such as esters and ketones. It is also a very strong nucleophile.

How do you Deprotonate an alkyne?

Not strongly acidic, mind you. But acidic enough. If you treat a “terminal alkyne” (an alkyne that ends in a C-H bond) with a strong base such as NaNH2, it will be deprotonated to form its conjugate base – called an “acetylide”.

What is the meaning of Sodamide?

sodamide in British English (ˈsəʊdəˌmaɪd ) a white crystalline compound used as a dehydrating agent, as a chemical reagent, and in making sodium cyanide. Formula: NaNH2. Also called: sodium amide.

How is Sodamide prepared?

Sodium amide can be prepared by the reaction of sodium with ammonia gas, but it is usually prepared by the reaction in liquid ammonia using iron(III) nitrate as a catalyst. The reaction is fastest at the boiling point of the ammonia, c. −33 °C. An electride, [Na(NH3)6]+e−, is formed as a reaction intermediate.

What is the function of NaNH2?

NaNH2 is a strong base and excellent nucleophile. It’s used for deprotonation of weak acids and also for elimination reactions. Its functions: As a strong base, NaNH2 will deprotonate alkynes, alcohols, and a host of other functional groups with acidic protons such as esters and ketones.

Will hydrofluoric acid dissolve a gun?

Hydrofluoric acid is very nasty stuff, but it isn’t a strong acid. Even when dilute it will etch glass and ceramics, but it won’t dissolve or burn flesh. Concentrated alkalis such as Sodium Hydroxide are readily available and are very good at dissolving flesh (which is why they are commonly used as drain cleaners).

How does Acid destroy tissue?

The corrosive action of acid on living tissues is due to the catalytic reaction of acid-base in ester and amide hydrolysis. The corrosive acids will react with the skin and hydrolyze the fats which are the chemical forms of esters. Proteins in the skin exist as amides and they are hydrolyzed by acid-base catalysis.