What is the role of IGF 1?

What is the role of IGF 1?

IGF-1 then stimulates systemic body growth, and has growth-promoting effects on almost every cell in the body, especially skeletal muscle, cartilage, bone, liver, kidney, nerve, skin, hematopoietic, and lung cells. In addition to the insulin-like effects, IGF-1 can also regulate cellular DNA synthesis.

Is IGF 1 safe to use?

The U.S. Anti-Doping Agency warns that products that say they contain IGF-1 may not. The side effects of IGF-1 may be similar to those of other growth hormones. These include overgrowth of body tissues, known as acromegaly, and damage to the joints, liver, and heart. IGF-1 can cause your blood glucose levels to drop.

Does insulin increase IGF 1?

Insulin resistance is highly correlated to obesity and high insulin levels as insulin stimulates hepatic IGF-I synthesis (34) and increases the fraction of circulating free IGF-I by downregulating hepatic synthesis of IGFBP-1 and, to a lesser extent, hepatic secretion of IGFBP-2 (35,36).

Is IGF 1 banned in military?

Use of IGF-1 products is banned by the United States Anti-Doping Agency, World Anti-Doping Agency, and most professional sports organizations. IGF-1 is also on the OPSS list of DoD-prohibited substances, so Military Service Members should avoid products with this ingredient.