What happens if you accidentally take too much Wellbutrin?
What happens if you accidentally take too much Wellbutrin?
In severe toxic doses it can cause coma, hypotension, multiple seizures, QRS widening, QTc prolongation, status epilepticus, and ventricular dysrhythmias [2]. Seizure due to intentional or unintentional overdose is among the most commonly reported toxic effect of bupropion [3–6].
What happens if you take 900 mg of Wellbutrin?
Conclusion: After an overdose of bupropion, clinical effects are seen primarily on the neurological, cardiovascular, and gastrointestinal systems. Neurological effects can include tremor, confusion, agitation, hallucinations, coma, and seizures.
How much Wellbutrin is too much?
Maximum dosage: 450 mg per day, taken in divided doses of no more than 150 mg each. Your doctor may prescribe this dosage for you if you don’t respond to several weeks of treatment.
What is considered an overdose of bupropion?
Seizures are a hallmark of toxicity Bupropion lowers the seizure threshold, even at therapeutic doses of 150–450 mg/d. Acute overdose typically produces seizures within a few hours after ingestion, although seizure onset may be delayed up to 24 hours in patients who ingest extended-release preparations.
Can I take 2 bupropion XL 150 mg?
The dose for smoking cessation is bupropion SR 150 mg once daily for 3 days and then twice daily for 7 to 12 weeks. You should not take more than one product that contains bupropion, including the products that are used to quit smoking.
How common are seizures on Wellbutrin?
The seizure incidence in patients taking ≤ 450 mg per day of bupropion IR is 0.4%, while the incidence in those taking 600 to 900 mg per day is 2.8%. This elevated risk of seizure led to a lowering of the maximum dose and the development of sustained- and extended-release products.
Can I cut Wellbutrin XL in half?
How are they taken? Wellbutrin SR and XL are taken according to the following dosing instructions, with or without food. Swallow the tablets whole and don’t crush, split, or chew them.
Is Wellbutrin good for weight loss?
Though most antidepressants can cause weight gain, bupropion is a medication for depression that can lead to weight loss. If people with depression are concerned about weight gain, this might be a suitable option. People who do not have depression should not take bupropion to lose weight.
Can you overdose on Wellbutrin 300mg?
An overdose of Wellbutrin XL can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.
How often does Wellbutrin cause false positive?
A case report also described a patient taking 300 mg of bupropion daily and testing falsely positive for amphetamines. A reference test, which added bupropion to drug-free urine, showed that the cross-reactivity of bupropion with the amphetamine immunoassay ranged from 3% to 17%, depending on concentration.