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Is HLA-B27 rare?

Joe Ford

Is HLA-B27 rare?

HLA-B27 is rare in the American black population whereas Eskimo populations carry it much more frequently than Western Europeans, with prevalence rates of 25% or more. This antigen is associated with ankylosing spondylitis in virtually all racial groups studied.

What should you not do if you have ankylosing spondylitis?

But even if you take prescribed medication to improve your quality of life, there are a few lifestyle choices that may worsen symptoms.

  • Sedentary lifestyle.
  • Poor posture.
  • Smoking.
  • Doing too much.
  • Not taking medication as directed.
  • Being overweight.
  • Lack of sleep.
  • Chronic stress.

What is the main cause of ankylosing spondylitis?

Ankylosing spondylitis has no known specific cause, though genetic factors seem to be involved. In particular, people who have a gene called HLA-B27 are at a greatly increased risk of developing ankylosing spondylitis. However, only some people with the gene develop the condition.

What supplements to take for ankylosing spondylitis?

“People with ankylosing spondylitis can help maintain their bone health with calcium and vitamin D supplements,” Dr. Tehrani says.

How does ankylosing spondylitis affect the kidneys?

In this case, patients can develop shortness of breath, dizziness, and heart failure. Advanced spondylitis can lead to deposits of protein material called amyloid into the kidneys and result in kidney failure.

How does ankylosing spondylitis affect the heart?

A Canadian study showed that ankylosing spondylitis (AS) increases the risk for heart disease and stroke by anywhere from 25 to 60 percent, particularly for people 20 to 39 years old. AS raises the risk for many types of heart disease, including heart attack, chest pain, valve disease, heart failure, and stroke.

Can ankylosing spondylitis cause brain fog?

While not an actual medical condition, brain fog is a symptom of chronic arthritis conditions like ankylosing spondylitis. Without getting too technical, during an AS symptom flare, signals to and from pain receptors interfere with normal brain function.