Does clopidogrel affect the kidneys?

Does clopidogrel affect the kidneys?

In summary, among patients hospitalized with ACS and treated with clopidogrel, lower levels of kidney function were associated with a greater risk of death, hospitalization for AMI, and major bleeding.

Can I drink coffee with clopidogrel?

Conclusions: Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.

What is the best antiplatelet drug?

Clopidogrel (75 mg daily) is the preferred antiplatelet. If intolerant of clopidogrel, aspirin in combination with modified-release dipyridamole (200 mg twice a day).

Is clopidogrel safer than aspirin?

CAPRIE: clopidogrel versus aspirin Clopidogrel reduced the annual risk of such a vascular event from 5.83 to 5.32% in comparison with aspirin, corresponding to a relative risk reduction (RRR) of 8.7%. The 95% confidence interval just kept clear of the neutral value and ranged from 0.3 to 16.5%.

Which is better aspirin or clopidogrel?

Clopidogrel is another guideline‐recommended antiplatelet agent21 and has been shown to be superior to aspirin in preventing composite vascular events and reducing hemorrhagic complications in a randomized controlled trial, CAPRIE (Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events).

Is aspirin and Ecosprin same?

Ecosprin contains Aspirin as the active pharmaceutical ingredient. Aspirin belongs to the class NSAIDS (Non-steroidal and anti-inflammatory drug). Ecosprin has antiplatelet action and prevents the formation of blood clots.

How long should I stay on clopidogrel?

The optimal duration of dual antiplatelet therapy is not known; 12 months has been the commonly recommended duration. A recent large trial changed recommendations. Rates of stent thrombosis and death from stroke or heart attack were lower when the two meds were continued for 18 more months.

Is clopidogrel same as aspirin?

Aspirin and Plavix (clopidogrel bisulfate) are drugs used to prevent blood clots. Aspirin and Plavix belong to different drug classes. Plavix is an anticoagulant and aspirin is a nonsteroidal anti-inflammatory drug (NSAID). Aspirin also is used to reduce fever, and to treat pain and inflammation in the body.

Why is clopidogrel and aspirin used together?

The combination of clopidogrel and aspirin may lower the risk for major ischemic events among patients with minor ischemic stroke or high-risk transient ischemic attack compared with aspirin alone, according to results of the POINT study.

Does clopidogrel lower blood pressure?

You likely won’t have blood pressure changes while you’re taking Plavix. However, sudden drops in blood pressure may be a symptom of serious internal bleeding, which is a possible side effect of Plavix.

What blood pressure medication causes hair loss?

Blood pressure medications Beta blockers, including the following, can cause hair loss: metoprolol (Lopressor) timolol (Blocadren) propranolol (Inderal and Inderal LA)

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel. Acute-phase reactants were elevated.

What should you not take with clopidogrel?

Clopidogrel may interact with other medications

• Diabetes drug. In most cases, repaglinide should not be taken with clopidogrel.
• Stomach acid drugs (proton pump inhibitors)
• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Blood thinners.
• Drugs used to treat depression.
• Salicylates (aspirin)
• Opioids.

What vitamins should be avoided when on blood thinners?

“Patients on the blood thinners Coumadin or Warfarin need to avoid vitamin K-rich foods and supplements,” said Dr. Samantha Crites, a cardiologist at Mon Health Heart and Vascular Center. “While blood thinners prevent and/or dissolve blood clots, Vitamin K can thicken your blood.”

Can I take vitamin C with clopidogrel?

Interactions between your drugs No interactions were found between clopidogrel and Vitamin C.

Is atorvastatin a blood thinner?

The short answer is YES, but very little. Cholesterol lowering drugs, often called “statins” are intended to lower an important component of your total blood cholesterol, the LDL or “low density lipoproteins”.

What are the long term side effects of atorvastatin?

What are statin side effects?

• Muscle pain and damage. One of the most common complaints of people taking statins is muscle pain.
• Liver damage. Occasionally, statin use could cause an increase in the level of enzymes that signal liver inflammation.
• Increased blood sugar or type 2 diabetes.
• Neurological side effects.

What foods should be avoided when taking atorvastatin?

A: While taking atorvastatin (Lipitor), avoid high-fat and high-cholesterol foods as part of your overall treatment. You should avoid large quantities of grapefruit or grapefruit juice, which can increase the risk of serious side effects. Also, avoid excess alcohol use, as this may cause serious liver problems.

Can I eat oranges while taking atorvastatin?

Be mindful that other citrus fruits might also interact with lovastatin, atorvastatin, and simvastatin. The list includes tangelos, pomelos, bitter oranges, and Seville oranges. These foods can also affect how your body metabolizes the medication.

What fruit can’t you eat with statins?

Grapefruit and statins: Eating grapefruit, either the fruit itself or as juice, can slow the body’s ability to metabolize statin cholesterol-lowering drugs, which include Lipitor, Crestor and Zocor.

Can I take vitamin D with atorvastatin?

No interactions were found between atorvastatin and Vitamin D3. This does not necessarily mean no interactions exist.

Does vitamin D increase cholesterol?

Population studies show that people with lower vitamin D levels are more likely to have high cholesterol, although this doesn’t prove a “cause and effect” relationship. One 2012 study found that vitamin D supplements have no cholesterol-lowering effects, at least in the short term.

Does B12 lower cholesterol?

They found that low levels of vitamin B12 were associated with higher levels of total cholesterol, LDL (bad) cholesterol, and triglycerides—even after adjusting for the effects that body mass index, abdominal fat, and total body fat percentage have on the body.

Can I take zinc with atorvastatin?

No interactions were found between atorvastatin and Vitamin C plus Zinc.